Does lack of sleep aggravate acne? This is one of the questions bugging me as I haven’t been getting enough rest lately. Ugh, I even slept at four in the wee hours of the morning yesterday. They say lack of sleep can cause skin to become oily and prone to adult acne. I also think stress is one of the main causes for problems in facial skin condition. As they say, worrying and being anxious can aggravate acne. There’s even a joke that you could be frustrated about love if you have a big red pimple on your face. True or not?